Tools of the trade: Duo Quattro PRF Centrifuge


by Dr Andrew See, See The Dentist, Hunters Hill, NSW

This centrifuge is used to spin patient’s blood and separate it into red blood cells, acellular plasma and the fibrin clot. This fibrin network acts as a reservoir of tissue growth factors. 

What’s good about it

Once the blood is separated you can collect the portion of the fibrin clot that contains the leukocytes and platelets rich in growth factors. These growth factors promote proliferation and differentiation of osteoblasts, endothelial cells, chondrocytes, and various sources of fibroblasts. Platelet Rich Fibrin (PRF) can be used as a membrane, gel, plug or mixed with bone substitutes to make ‘sticky bone’. 

It can be placed into extraction sockets and during bone grafting, or used with soft tissue healing. It encourages revascularisation so the healing is much faster compared to not adding it.

I’ve been getting very good healing results for repair/regeneration of soft and hard tissues. 


There were times when I did socket grafting where biomaterials such as donated cadaver bone, or even cow bone, was put into the socket. Now I use PRF plugs. The PRF is made from the patient’s own blood so it’s very biocompatible, readily available, easy to prepare and there is no risk of a foreign body response. The PRF clot holds the space and encourages quicker healing.

What’s not so good

As you are extracting blood, you or a member of your staff have to complete an accredited venipuncture course. The other option is to have a sedationist or anaesthetist collect the blood.

Where did you get it


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