New gel whitens teeth without the burn

whitening gel hydroxyl radicals
Photo: subbotina 123rf

Unfortunately, the high levels of hydrogen peroxide in dentists’ bleaching treatments can damage enamel and cause tooth sensitivity and gum irritation. Now, researchers from China have developed a gel that, when exposed to near infrared (NIR) light, safely whitens teeth without the burn.

Tooth whitening treatments at a dentist’s office are effective, but they use high-concentration hydrogen peroxide. Home bleaching products contain less peroxide but they usually require weeks of treatment and don’t work as well. 

When a bleaching gel is applied to teeth, hydrogen peroxide and peroxide-derived reactive oxygen species (mainly the hydroxyl radical) degrade pigments in stains. The hydroxyl radical is much better at doing this than hydrogen peroxide itself, so researchers have tried to improve the bleaching capacity of low-concentration hydrogen peroxide by boosting the generation of powerful hydroxyl radicals. 

Because previous approaches have had limitations, researchers from Sichuan University wanted to develop a safe, effective whitening gel containing a catalyst that, when exposed to NIR light, would convert low levels of hydrogen peroxide into abundant hydroxyl radicals.

The researchers—reporting in ACS Applied Materials & Interfaces—made oxygen-deficient titania nanoparticles that catalysed hydroxyl radical production from hydrogen peroxide. Exposing the nanoparticles to NIR light increased their catalytic activity, allowing them to completely bleach tooth samples stained with orange dye, tea or red dye within two hours. 

Then, the researchers made a gel containing the nanoparticles, a carbomer gel and 12 per cent hydrogen peroxide. They applied it to naturally stained tooth samples and treated them with NIR light for an hour. The gel bleached teeth just as well as a popular tooth whitening gel containing 40 per cent hydrogen peroxide, with less damage to enamel.

The nanoparticle system is highly promising for tooth bleaching and could also be extended to other biomedical applications, such as developing antibacterial materials, the researchers said.


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